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Acyl Carnitine Lipids


A87855 3-Me-Glutaryl Carnitine

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A87873 Adipoyl-L-carnitine

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A87337 C10:0 L-carnitine (HCl salt)

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A87871 C12:1 L-carnitine (HCl salt)

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A87850 C12 Carnitine

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A87867 C14:1 L-carnitine (HCl salt)

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A87854 C14 Carnitine (HCl salt)

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A87869 C15:0 L-carnitine (HCl salt)

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A87863 C16:0(alkyne) L-carnitine

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A87851 C16 Carnitine

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A87852 C18:1(Δ9-cis) Carnitine

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A87881 C18:2 L-carnitine, HCl salt

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A87859 C2:0 L-carnitine (HCl salt)

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A87870 C4:0 L-carnitine (HCl salt)

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A87866 C5:0 L-carnitine (HCl salt)

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A87862 C8:0 L-carnitine

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A87875 Malonyl-L-carnitine

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A87864 pacFA L-carnitine

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Acylcarnitines are acyl esters of the quaternary ammonium compound carnitine. These esters are essential for the catabolism of fatty acids and maintenance of energy homeostasis in the human body. Acylcarnitines transport acyl groups from fatty acids into the mitochondria to generate energy. These molecules are capable of moving through the mitochondrial and cell membranes via a carnitine shuttle. There are several disorders that have been linked to acylcarnitine metabolic defects including various acyl-CoA dehydrogenase deficiencies. These defects typically manifest as encephalopathy, cardiomyopathy, and myopathy. Milder acylcarnitine abnormalities have been detected in diseases such as insulin resistance, cardiovascular disease, and Alzheimer's disease.

https://www.lipidmaps.org/resources/lipidweb/lipidweb_html/lipids/simple/carnitin/index.htm

Gerald Liew, Benita Tse, I-Van Ho, Nichole Joachim, Andrew White, Russell Pickford, David Maltby, Bamini Gopinath, Paul Mitchell, Ben Crossett; Acylcarnitine Abnormalities Implicate Mitochondrial Dysfunction in Patients With Neovascular Age-Related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2020;61(8):32. DOI: https://doi.org/10.1167/iovs.61.8.32.