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Endocannabinoids/Anandamides


800740 N-16:0 L-Serine

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800730 N-16:0 L-Serine MeEster

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800732 N-20:4 L-Serine MeEster

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800741 N-18:1 L-Serine

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800742 N-20:4 L-Serine (ARA-S)

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810106 NBD AA

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857465 AEA-d4

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861810 arachidonic acid-d11

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870430 C20:4 anandamide (AEA)

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870431 C17:1 anandamide

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870432 C18:1 anandamide

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870437 C17:0 anandamide phosphate

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870439 C18:2 anandamide phosphate

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870450 2-AG

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870451 2-OG

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872120 18:1 PE-N-16:0

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872100 18:1 PE-N-20:4

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872101 16:0-20:4 PE-N-20:4

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Endocannabinoids are endogenous cannabis-like substances that play a vital role in the endogenous cannabinoid system. This system is a lipid signaling system that regulates many bodily functions in all vertebrates. These endocannabinoids are small molecules derived from arachidonic acid, anandamide, and 2-arachidonoylglycerol. These molecules bind to a family of GPCR’s in areas of the brain related to motor control, cognition, emotion, behavior, and homeostasis. Outside of the brain, endocannabinoids are modulators of the autonomic nervous system, immune system, and microcirculation. The study of endocannabinoids has been linked to further understanding the physiological role that these molecules play and the treatment of pain, obesity, neurological diseases, and drug addiction.

Fernando Rodríguez De Fonseca, Ignacio Del Arco, Francisco Javier Bermudez-Silva, Ainhoa Bilbao, Andrea Cippitelli, Miguel Navarro, The Endocannabinoid System: Physiology and Pharmacology, Alcohol and Alcoholism, Volume 40, Issue 1, January/February 2005, Pages 2-14, Https://Doi.Org/10.1093/Alcalc/Agh110