Mixed Acyl

A85445 14:0-16:0 PC

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A85446 14:0-18:0 PC

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A83716 15:0-18:1 PC

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A88622 16:0-02:0 PC

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A80420 16:0-(12-PAHSA) PC

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A85454 16:0-14:0 PC

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A85456 16:0-18:0 PC

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A80557 16:0-18:1 PC (POPC)

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A85458 16:0-18:2 PC

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A85459 16:0-20:4 PC

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A85461 16:0-22:6 PC

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A85764 18:0-14:0 PC

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A85765 18:0-16:0 PC

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A85467 18:0-18:1 PC

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A85468 18:0-18:2 PC

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A85469 18:0-20:4 PC

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A85470 18:0-22:6 PC

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A85473 18:1-14:0 PC

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A85475 18:1-16:0 PC

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A85485 18:1-18:0 PC

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A86804 PGPC-d5

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PC & LPC

Phosphatidylcholine (PC) was first found to be a component of egg yolk and originally called “lecithin”. PC is the most abundant phospholipid in cells and positively influences the incorporation of cholesterol in membranes. Sphingomyelin synthesis is also dependent on its PC precursor. PC has been linked to several biological processes including intracellular cholesterol transport and membrane cholesterol homeostasis. Other roles include membrane-mediated cell signaling and PCTP activation of enzymes.

Lysophosphatidylcholine (LPC) has increasingly gained recognition as a factor associated with cardiovascular and neurodegenerative diseases. LPC is primarily produced by PC turnover via phospholipase A2. LPC is recycled to PC when Acyl-CoA is available in the presence of lysophosphatidylcholine acyltransferase (LPCAT). Research is currently being conducted to better understand enzyme kinetics and LPC metabolism to identify possible therapeutic targets for LPC-associated diseases.

Lagace TA. Phosphatidylcholine: Greasing the Cholesterol Transport Machinery. Lipid Insights. 2016;8(Suppl 1):65-73. Published 2016 Apr 4. doi:10.4137/LPI.S31746

Law SH, Chan ML, Marathe GK, Parveen F, Chen CH, Ke LY. An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases. Int J Mol Sci. 2019;20(5):1149. Published 2019 Mar 6. doi:10.3390/ijms20051149

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Mixed Acyl

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