16:0 Lyso PC-D9 870310 1-hexadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine(d9)

16:0 Lyso PC, also known as 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine, is a remarkable phospholipase-mediated hydrolyzed phosphocholine. This lipid features a saturated fatty acid—palmitic acid (16:0)—as its tail, which is generated through the hydrolysis of the sn-2 acyl chain of phosphatidylcholine (PC) by phospholipase A2. A crucial component of oxidized low-density lipoprotein, 16:0 Lyso PC plays a significant role in inflammatory diseases and atherosclerosis and is a substrate for Autotaxin/LysoPLD, generating lysophosphatidic acid, which is essential for cell motility. The versatility of 16:0 Lyso PC makes it a powerful tool in various advanced research and therapeutic applications. In microbubble-mediated drug delivery, it enhances the efficiency of targeted therapy applications, particularly in cancer treatment. By integrating into microbubble technologies, 16:0 Lyso PC facilitates precise drug delivery to target sites, optimizing therapeutic outcomes.

Furthermore, its application in photodynamic therapy for glioma underscores its potential in medical treatments. Research has highlighted its role in biohybrid systems for light-activatable therapies, showing promise in treating challenging conditions like glioma. This innovative approach leverages 16:0 Lyso PC to improve clinical outcomes, showcasing its potential to enhance the effectiveness of photodynamic therapy. This product is deuterated which enables the study of structure, dynamics, and function of cell membranes.