Fixed Cationic Lipids

A89700 12:0 EPC (Cl Salt)

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A89701 14:0 EPC (Cl Salt)

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A89860 14:0 TAP

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A89717 14:1 EPC (Tf Salt)

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A89705 16:0-18:1 EPC (Cl Salt)

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A86775 16:0 CB (DPCB)

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A89702 16:0 EPC (Cl Salt)

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A86776 16:0 SB (DPSB)

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A89870 16:0 TAP

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A80810 18:0 DDAB

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A89703 18:0 EPC (Cl Salt)

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A89880 18:0 TAP

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A89704 18:1 EPC (Cl Salt)

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A80890 18:1 TAP (DOTAP)

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A89895 18:1 TAP (DOTAP, MS Salt)

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A89718 APL-718

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A89719 APL-719

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A89200 DC-6-14

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A85310 DOBAQ

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A85549 DORI

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A89898 DOTMA

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A81890 Fluorescent DOTAP

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A89326 Fluorescent Transfection Reagent

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A89310 Transfection Reagent I

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Nucleic acid delivery is a focus area for therapeutic research across the globe. Nucleic acid cargo such as DNA, mRNA, siRNA, and CRISPR/Cas-9 gene editing technologies are negatively charged (anionic) and thus, to sequester and deliver the cargo, the delivery system needs a positively charged (cationic) component. Unlike ionizable lipids, fixed cationic lipids are constantly charged in biological environments regardless of the pH.

Fixed cationic lipids have been proven to be good transfection agents in liposomes and lipid nanoparticles. Generally considered non-toxic at lower concentrations, these lipids do present some toxicity concerns when used in higher concentrations due to the tetra substituted ammonium moiety. Avanti offers a wide range of proven fixed cationic lipids such as DOTMA or DOTAP, but new, innovative cationic lipids are constantly being added. Check out our fixed cationic lipid offerings and fuel your lipid-based nucleic acid delivery research today!

High Purity Cationic Lipids for Liposomal Transfection Research

With their versatile transfection uses, cationic lipids serve liposomal research well. Let Avanti cater to your specific R&D with our diverse offerings.

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Certest Lipids

Our partnership with Certest is advancing lipid-based delivery solutions through cutting-edge ionizable lipid technologies. This collaboration allows us to develop innovative lipids that passively target the lungs, liver, and spleen, enhancing therapeutic precision and minimizing off-target effects. By combining Certest’s expertise with Avanti Research’s commitment to quality and innovation, we’re driving the future of targeted drug delivery.

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Ionizable lipids for your nucleic acid delivery research

Explore Avanti Research’s high-purity ionizable lipids for mRNA, siRNA, and gene delivery. Engineered for optimal pKa and endosomal escape to support your research.

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