Fixed Cationic Lipids

A89700 (890700) 12:0 EPC (Cl Salt)

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A89701 (890701) 14:0 EPC (Cl Salt)

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A89860 (890860) 14:0 TAP

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A89717 (890717) 14:1 EPC (Tf Salt)

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A89705 (890705) 16:0-18:1 EPC (Cl Salt)

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A86775 (860775) 16:0 CB (DPCB)

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A89702 (890702) 16:0 EPC (Cl Salt)

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A86776 (860776) 16:0 SB (DPSB)

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A89870 (890870) 16:0 TAP

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A80810 (890810) 18:0 DDAB

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A89703 (890703) 18:0 EPC (Cl Salt)

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A89880 (890880) 18:0 TAP

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A89704 (890704) 18:1 EPC (Cl Salt)

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A80890 (890890) 18:1 TAP (DOTAP)

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A89895 (890895) 18:1 TAP (DOTAP, MS Salt)

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A89718 (890718) APL-718

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A89719 (890719) APL-719

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A89200 (890200) DC-6-14

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A85310 (850310) DOBAQ

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A85549 (850549) DORI

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A89898 (890898) DOTMA

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A81890 (810890) Fluorescent DOTAP

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A89326 (790326) Fluorescent Transfection Reagent

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A89310 (790310) Transfection Reagent I

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Nucleic acid delivery is a focus area for therapeutic research across the globe. Nucleic acid cargo such as DNA, mRNA, siRNA, and CRISPR/Cas-9 gene editing technologies are negatively charged (anionic) and thus, to sequester and deliver the cargo, the delivery system needs a positively charged (cationic) component. Unlike ionizable lipids, fixed cationic lipids are constantly charged in biological environments regardless of the pH.

Fixed cationic lipids have been proven to be good transfection agents in liposomes and lipid nanoparticles. Generally considered non-toxic at lower concentrations, these lipids do present some toxicity concerns when used in higher concentrations due to the tetra substituted ammonium moiety. Avanti offers a wide range of proven fixed cationic lipids such as DOTMA or DOTAP, but new, innovative cationic lipids are constantly being added. Check out our fixed cationic lipid offerings and fuel your lipid-based nucleic acid delivery research today!

Cationic Lipids for Liposomal Transfection

With their versatile transfection uses, cationic lipids serve liposomal research well. Let Avanti cater to your specific R&D with our diverse offerings.

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Certest Lipids

Our partnership with Certest is advancing lipid-based delivery solutions through cutting-edge ionizable lipid technologies. This collaboration allows us to develop innovative lipids that passively target the lungs, liver, and spleen, enhancing therapeutic precision and minimizing off-target effects. By combining Certest’s expertise with Avanti Research’s commitment to quality and innovation, we’re driving the future of targeted drug delivery.

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Ionizable lipids for your nucleic acid delivery research

Explore Avanti Research’s high-purity ionizable lipids for mRNA, siRNA, and gene delivery. Engineered for optimal pKa and endosomal escape to support your research.

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