IsoPure: Isomerically Pure Mixed-Acyl Glycerophospholipids

A89454 16:0-18:1(n10) PC - IsoPure

Buy now

A89455 16:0-18:1(n7) PC - IsoPure

Buy now

A89453 16:0-18:1(n9) PC - IsoPure

Buy now

A89518 16:0-18:1(n9) PE - IsoPure

Buy now

A89520 16:0-18:1(n9) PG - IsoPure

Buy now

A89522 16:0-18:1(n9) PS-IsoPure

Buy now

A89574 16:0-18:1 Phosphatidylethanol-IsoPure

Buy now

A89524 16:0-20:4 PC - IsoPure

Buy now

A89575 18:1-16:0 Phosphatidylethanol-IsoPure

Buy now

A89457 18:1(n10)-16:0 PC - IsoPure

Buy now

A89456 18:1(n7)-16:0 PC - IsoPure

Buy now

A89458 18:1(n9)-16:0 PC - IsoPure

Buy now

A89519 18:1(n9)-16:0 PE - IsoPure

Buy now

A89521 18:1(n9)-16:0 PG-IsoPure

Buy now

A89523 18:1(n9)-16:0 PS - IsoPure

Buy now

A89485 20:4-16:0 PC - IsoPure

Buy now

A89525 TopFluor-20:4 PC - IsoPure

Buy now

IsoPure

Mixed-acyl glycerophospholipids are among the most abundant lipids in nature. Famously, 1-palmitoyl-2-oleoyl phosphatidylcholine (POPC) is the most abundant phospholipid in most eukaryotic cells and tissues. The molecular structure of POPC follows the textbook consensus that unsaturated fatty acyl chains occupy the sn-2 position of the glycerol backbone while saturated fatty acyl chains are relegated to the sn-1 position. As our analytical technologies advance, this conventional wisdom is being turned inside out with the isomer 1-oleoyl-2-palmitoyl phosphatidylcholine (OPPC) being identified at high abundance in samples ranging from plasma to tissue [1,2,3]. Adding to the complexity, both isomers are present in many instances in ratios ranging from 1:100 to 1:1. Resolving the puzzle of lipid isomers requires advanced analytical tools in conjunction with structurally defined reference materials. Until recently, commercially available synthetic lipids were also comprised of mixtures, as transacylation occurring in the round-bottom flask always led to 10-20% OPPC in any preparation of POPC. Moreover, the regiopurity of the product was difficult to define. Avanti has now introduced the IsoPure line wherein innovative synthetic procedures produce mixed-acyl glycerophospholipids with >97% regiopurity. These next-generation standards will be pivotal to isomer-resolved identification of glycerophospholipids in biological samples.

Browse our line of IsoPure phospholipids below and find ordering information here.

[1] Ekroos K, Ejsing CS, Bahr U, Karas M, Simons K, Shevchenko A. Charting molecular composition of phosphatidylcholines by fatty acid scanning and ion trap MS3 fragmentation. J. Lipid Res. 2003, 44, 2181. PMID: 12923235

[2] Zacek P, Bukowski M, Rosenberger TA, Picklo M. Quantitation of isobaric phosphatidylcholine species in human plasma using a hybrid quadrupole linear ion-trap mass spectrometer. J. Lipid Res. 2016, 57, 2225. PMID: 27688258

[3] Maccarone AT, Duldig J, Mitchell TW, Blanksby SJ, Duchoslav E, Campbell JL. Characterization of acyl chain position in unsaturated phosphatidylcholines using differential mobility-mass spectrometry.J. Lipid Res. 2014, 55, 1668. PMID: 24939921

Name	Typical content	Expires
cookieConsent	Used to check if your device accepts cookies and used to remember users cookie consent.	1 year
ASP.NET_SessionId	This cookie is used by ASP.NET to maintain an anonymous user session by assigning a unique session ID. It enables the website to store temporary information between pages, such as login status or form input.	End of session
commerceCart	Used to store items added to a cart by an anonymous user. Contents are serialized.	7 days
.AspNet.Cookies	This cookie is used to identify and authenticate logged-in users. It maintains secure sessions by storing an encrypted authentication token.	30 days
SC_ANALYTICS_GLOBAL_COOKIE	This analytics cookie is provided by Sitecore. It tracks a visitor’s multiple visits to our Website in one year. We use this information to help improve our Website. This cookie is not used to identify individuals using the Website.	10 Years
sitename#lang	This cookie is provided by Sitecore. This cookie tracks a user's language selection. The name of the cookie varies based on the configured site name	End of Session
shell#lang	This cookie is provided by Sitecore. This cookie tracks a user's language selection. The name of the cookie varies based on the configured site name	End of Session
__RequestVerificationToken	An anti forgery token used to help prevent CSRF attacks.	End of Session
_form_goals	Used to check if you have previously complete a form.	2 years
lastShownMarketingConsentDate_{identifier}	Use to determine when we requested you review your marketing consent for your account. It helps ensure we limit prompting to review your marketing consent, improving user experience.	1 year
mailinglistsignupbanner_{identifier}	Use to determine when whether a mailing list sign up form has been already shown within a time period. It helps ensure that users are not repeatedly prompting or shown sign up forms, improving user experience. We may create multiple cookies with different identifiers.	< 120 days
productFinderLastSearch	Used within our product finder to determine the last search performed.	1 year
purchaseRegion	This cookie will be used to determine the purchase region	30 days
VISITOR_PRIVACY_METADATA	YouTube sets this cookie to store the user's cookie consent state for the current domain.	6 months

Name	Typical content	Expires
recentlyViewedItems	Contains a list of recently visited items including products or formulations.	30 days
li_gc	Used by LinkedIn to store consent of guests regarding the use of cookies for non-essential purposes.	6 months
lidc	Used by LinkedIn for routing.	24 hours
__Secure-1PAPISID	Essential for maintaining your logged-in state (session) and authenticating you across different Google services securely.	2 years
__Secure-1PSID	Set by Google, this cookie works alongside others to verify your identity and keep you signed in to your Google account securely.	2 years
__Secure-1PSIDCC	A crucial security cookie used by Google to confirm the authenticity of the user's session, helping to protect users data from unauthorised access.	1 year
_bioz_depot_session	Bioz.com	Session

Name	Typical content	Expires
_gat	Used by Google Analytics to throttle request rate.	10 minutes
_ga	Contains a unique identifier used by Google Analytics to determine unique visitors to our website.	2 years
_clsk	Used by Microsoft Clarity to connect multiple page views by a user into a single Clarity session recording.	1 day
_clck	Persists the Microsoft Clarity User ID and preferences, unique to that site is attributed to the same user ID.	1 year
YSC	YSC cookie is set by Youtube and is used to track the views of embedded videos on Youtube pages.	Session
_uetsid	Bing Ads sets this cookie to engage with a user that has previously visited the website.	1 day
_uetvid	Bing Ads sets this cookie to engage with a user that has previously visited the website.	1 year 24 days
__Secure_ROLLOUT_TOKEN	Used by YouTube to manage feature rollout and experimentation. It helps Google control which new features or interface changes are shown to users as part of testing and staged rollouts, ensuring consistent experience for a given user during an experiment.	6 months
__Secure_YEC	Used to detect spam, fraud, and abuse to protect advertisers and YouTube creators	13 months

Name	Typical content	Expires
ANONCHK	Used by Microsoft Clarity and Microsoft Ads to store session ID for a users session to ensure that clicks are verified for reporting purposes and for personalisation.	10 mins
MUID	Identifies unique web browsers used by Microsoft. These cookies are used for advertising, site analytics, and other operational purposes.	1 year
SM	Used by Microsoft to synchronise the unique identifier across Microsoft domains for consistent user recognition and ad targeting.	End of session
MR	Used by Microsoft to support ad delivery and performance tracking.	7 days
CLID	Used by Microsoft Clarity to identify the first time a user visited any site using Clarity. Helps track user behaviour and engagement across sessions for analytics purposes.	1 year
AEC	Used by Google to ensure that requests during a browsing session are genuinely made by the user, helping to prevent malicious activity such as cross-site request forgery.	6 months
NID	Set by Google to store user preferences and personalise content, including ads on Google services. Also supports services like reCAPTCHA and SafeSearch settings.	6 months
IDE	Set by Google (DoubleClick), this cookie helps show relevant ads to users and measure the success of advertising campaigns.	13 months
DSID	Set by Google, this cookie remembers a user’s ad preferences and identifies when they are signed in on non-Google sites.	7–14 days
__Secure-3PAPISID	Set by Google, this cookie helps deliver personalised adverts based on a user’s browsing history and profile.	2 years
__Secure-3PSID	Set by Google, this cookie works with others to show targeted adverts on third-party websites.	2 years
__Secure-3PSIDCC	Set by Google, this cookie helps prevent advertising fraud and ensures adverts are shown securely and reliably.	1 year
__Secure-3PSIDTS	Set by Google, this cookie tracks when users interact with ads and content for better ad performance measurement.	2 years
sa_user_id	StackAdapt sets this cookie as a third party advertising cookie to record information about a user's website activity, such as the pages visited and the locations viewed, to enable us to provide users with interest-based content and personalised advertisements on external websites.	1 year
sa_user_id_v2	StackAdapt sets this cookie as a third party advertising cookie to record information about a user's website activity, such as the pages visited and the locations viewed, to enable us to provide users with interest-based content and personalised advertisements on external websites.	1 year
sa_user_id_v3	StackAdapt sets this cookie as a third party advertising cookie to record information about a user's website activity, such as the pages visited and the locations viewed, to enable us to provide users with interest-based content and personalised advertisements on external websites.	1 year
bcookie	LinkedIn sets this cookie from LinkedIn share buttons and ad tags to recognise browser IDs.	1 year

IsoPure: Isomerically Pure Mixed-Acyl Glycerophospholipids

Products

Phospholipids

Contact us