Acyl Carnitine - Deuterated

870857 24:0(d4) L-carnitine

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870327 C10:0 L-carnitine-d9 (HCl salt)

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870326 C12:0 L-carnitine-d9 (HCl salt)

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870325 C14:0 L-carnitine-d9

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870323 C16:0 L-carnitine-d9

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870324 C18:0 L-carnitine-d9 (HCl salt)

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870321 C18:1 L-carnitine-d9

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870322 C18:2 L-carnitine-d9

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870333 C2:0 L-carnitine-d9

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870856 C26 D,L-Carnitine-d9

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870332 C3:0 L-carnitine-d9 (HCl Salt)

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870331 C4:0 L-carnitine-d9

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870330 C5:0 L-carnitine-d9

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870329 C6:0 L-carnitine-d9

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870328 C8:0 L-carnitine-d9

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870311 L-carnitine-d9

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Acylcarnitines are acyl esters of the quaternary ammonium compound carnitine. These esters are essential for the catabolism of fatty acids and maintenance of energy homeostasis in the human body. Acylcarnitines transport acyl groups from fatty acids into the mitochondria to generate energy. These molecules are capable of moving through the mitochondrial and cell membranes via a carnitine shuttle. There are several disorders that have been linked to acylcarnitine metabolic defects including various acyl-CoA dehydrogenase deficiencies. These defects typically manifest as encephalopathy, cardiomyopathy, and myopathy. Milder acylcarnitine abnormalities have been detected in diseases such as insulin resistance, cardiovascular disease, and Alzheimer's disease. Avanti offers deuterated acylcarnitine derivatives for use as standards when studying these molecules and their biological roles.

https://www.lipidmaps.org/resources/lipidweb/lipidweb_html/lipids/simple/carnitin/index.htm

Gerald Liew, Benita Tse, I-Van Ho, Nichole Joachim, Andrew White, Russell Pickford, David Maltby, Bamini Gopinath, Paul Mitchell, Ben Crossett; Acylcarnitine Abnormalities Implicate Mitochondrial Dysfunction in Patients With Neovascular Age-Related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2020;61(8):32. doi: https://doi.org/10.1167/iovs.61.8.32.

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Acyl Carnitine - Deuterated

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