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18:0, 18:2 PI(3)P

18:0, 18:2 PI(3)P A89938 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho- (1'-myo-inositol-3'-phosphate) (ammonium salt)

18:0, 18:2 PI(3)P
18:0, 18:2 PI(3)P is a synthetic phosphoinositide featuring a saturated stearic acid at the sn-1 position and an unsaturated linoleic acid at the sn-2 position. PI(3)P is a critical signaling lipid enriched in early endosomes and the internal vesicles of multivesicular bodies (MVBs). It serves as a specific recognition site for proteins containing FYVE or PX domains. Additionally, PI(3)P is essential for the initiation of autophagy, marking the site of phagophore formation. This 18:0, 18:2 analog is ideal for studying these membrane dynamics and protein-lipid interactions in a controlled, defined system.
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