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N-DODECYL-ß-D-MALTOSIDE (DDM, 85%)

N-DODECYL-ß-D-MALTOSIDE (DDM, 85%) 250520

N-DODECYL-ß-D-MALTOSIDE (DDM, 85%)

This product is a more cost-effective alternative to Avandecrys DDM that can be used for membrane protein extraction and purification.
DDM is the most widely used detergent for the isolation and purification of GPCR’s.
In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form (see Related Products).

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