Glyco-γ-muricholic acid A80262 (Previously 700262) 5ß-cholanic acid-3α,6α,7α-triol N-(2-carboxymethyl)-amide

Glyco-γ-Muricholic Acid is a bile acid (BA) glycine conjugate and a human metabolite.

The compound is a derivative of the BA γ-Muricholic Acid, formed as a result of conjugation of the BA with the amino acid glycine, which happens in liver hepatocytes.

Muricholic acids are a family of BAs found as the major contents of bile in mice, where the name of the group comes from. They are present in small quantities in humans and other species. Low levels of muricholic acids are usually found in human urine.

Muricholic acids differ from the primary BAs in human bile, cholic, and chenodeoxycholic acid, by containing an additional hydroxyl group in their molecules.

The metabolites are mostly known as potent regulators of bile acid synthesis via a positive feedback mechanism.

Derivatives of muricholic acids, including Glyco-γ-Muricholic Acid, are suitable to include in various research projects related to human health and disease.

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