Farnesyl pyrophosphate, ammonium salt 700300 (E,E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate, ammonium salt
Farnesyl pyrophosphate ammonium salt, also known as FPP, is a biochemical compound that plays a critical role in the mevalonate pathway, which is responsible for the biosynthesis of sterols, isoprenoids, and other important lipids in living organisms.
This molecule is a type of isoprenoid pyrophosphate and is synthesized from isopentenyl pyrophosphate and dimethylallyl pyrophosphate through a series of enzymatic reactions.
FPP is essential for a wide range of biological functions, including protein prenylation, steroid hormone biosynthesis, and regulation of cell signaling pathways.
Uses of Farnesyl Pyrophosphate Ammonium SaltFarnesyl pyrophosphate ammonium salt is widely used in research as a substrate for enzymes such as farnesyltransferase, which plays a key role in protein prenylation.
FPP also serves as a precursor for the synthesis of other important molecules, such as geranylgeranyl pyrophosphate and coenzyme Q10.
FPP and PharmaceuticalsFarnesyl pyrophosphate ammonium salt (FPP) is an important molecule in the development of pharmaceuticals. One of its primary uses is as a target for drug development, particularly in the treatment of cancer.
FPP is involved in protein prenylation, a process that is critical for the growth and survival of cancer cells. Inhibitors of farnesyltransferase, the enzyme that uses FPP to prenylate proteins, have been developed and tested in clinical trials as a potential treatment for cancer.
FPP is also used in the synthesis of coenzyme Q10, a molecule with antioxidant properties that has been investigated as a potential therapy for a range of conditions, including heart disease and Parkinson's disease.