Farnesyl-L-cysteine 700308 (E,E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl-L-cysteine

Farnesyl-L-cysteine (Farnesyl-FC) is a naturally occurring lipid-derived compound that has gained considerable attention in recent years for its potential therapeutic applications. It is closely associated with isoprenylated protein methyltransferase (ICMT), an enzyme that plays a critical role in the maturation of several proteins. ICMT catalyzes the methylation of the C-terminal isoprenylcysteine residues of proteins such as Rho, Rac, and Rap, which are important regulators of cell signaling pathways. Farnesyl-FC is a product of this process and serves as a substrate for ICMT, making it an essential molecule for the proper functioning of the isoprenylation pathway.

Additionally, this molecule is a post-translational modification of several proteins that play crucial roles in various cellular processes, including signal transduction, cytoskeletal dynamics, and cell proliferation. Farnesyl-FC has been found to possess various bioactive properties, such as anti-inflammatory, antioxidant, and anti-cancer effects. Due to its unique chemical structure and biological activities, Farnesyl-FC has emerged as a promising candidate for the development of novel therapeutics for various diseases.

The molecular weight of Farnesyl-L-cysteine (Farnesyl-FC) is approximately 539.8 g/mol. This lipid-derived molecule consists of a farnesyl group, which is a 15-carbon isoprenoid unit, and a cysteine residue, which is linked via a thioether bond.