Facade™-EM: Two Dimensional Amphiphile 850522 3α-hydroxy-7α,12α-di-((O-ß-D-maltosyl)-2-hydroxyethoxy)-cholane

Facade™-EM (3α-hydroxy-7α,12α-di-((O-ß-D-maltosyl)-2-hydroxyethoxy)-cholane) is a two-dimensional amphiphile with hydrophobic and hydrophilic faces. With its divergence from the traditional one-dimensional polar-head/nonpolar-tail molecules, this new class of detergents has a superior ability to stabilize integral membrane proteins. Keep reading to learn more.

One of the main challenges in protein biochemistry is the study of membrane proteins. This is especially true when working outside of the parameters of the natural lipid environment. When conducting in vitro studies, researchers rely heavily on the solubilization of membrane proteins—which typically requires wisely-chosen solubilizing detergents and mixed lipid/detergent systems.

Browse our entire catalog of detergents here