C18:0-d7 GM2 Ceramide (d18:1/18:0-d7), synthetic A86121 (Previously 860121) C18:0-d7 GM2 Ganglioside (GalNAcb1,4(Neu5Aca2,3)Galb1,4Glcb-Ceramide(d18:1/18:0-d7))

C18:0-d7 GM2 ceramide (d18:1/18:0-d7), also known as C18:0-d7 GM2 ganglioside or C18:0-d7 GM2 ganglioside (GalNAcb1,4(Neu5Aca2,3)Galb1,4Glcb-Ceramide(d18:1/18:0-d7)), is a synthetic, deuterium-labeled analog of the naturally occurring GM2 ganglioside. This compound features a sphingosine backbone (d18:1), a stearoyl fatty acid chain labeled with seven deuterium atoms (18:0-d7), and an oligosaccharide chain that includes a sialic acid (Neu5Ac) residue linked to an N-acetylgalactosamine (GalNAc) residue.

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Product details

Product Type

Lipids

Product Category

Sphingolipids - Glycosphingolipids - Gangliosides
Sphingolipids - Isotope Labeled - Gangliosides
Stable Isotopes & ESR Probes - Sphingolipids - Deuterated - Gangliosides
Stable Isotopes & ESR Probes - Sphingolipids - Deuterated

Application

GM2 gangliosides are primarily found in the nervous system and are critical to the structure and function of neuronal cell membranes. They play a key role in modulating cell signaling, particularly in the brain, where they influence neuronal growth, differentiation, and synaptic function. GM2 is also a key molecule involved in lysosomal storage diseases such as Tay-Sachs disease, making it a significant focus in neurodegenerative research. The deuterium labeling (d7) in this synthetic version allows for precise tracking in metabolic studies and provides an essential tool for researchers investigating the role of GM2 in cellular processes and disease mechanisms, particularly in the context of neurodegenerative disorders.

Data

Hygroscopic	No
Light sensitive	No
Molecular formula	C₆₇H₁₁₄D₇N₃O₂₆
Percent composition	C 57.82%, H 9.27%, N 3.02%, O 29.89%
Purity	97%
Stability	1 Year
Storage temperature	-20°C
CAS number	3056013-65-8 CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula weight	1391.74
Exact mass	1390.87

Certificates of Analysis

860121 - ChemDraw File
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ChemDraw File

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860121W - Safety Data Sheet
English: 529.0 KB

Safety Data Sheet

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