C18:0 Fuc-GM1 Ceramide (d18:1/18:0), synthetic A86143 (Previously 860143) C18:0 Fuc-GM1 Ganglioside ((Fuca1,2)Galb1,3GalNAcb1,4(Neu5Aca2,3)Galb1,4Glcb-Ceramide(d18:1/18:0))
C18:0 Fuc-GM1 Ceramide (d18:1/18:0) is a ganglioside that is a tumor associated antigen expressed in large amounts in patients with small cell lung cancer, but is completely absent in normal lung cells. This makes this ganglioside a promising target for immunoncology. By changing the chain length of the fatty acid portion of this ganglioside, it changes its membrane packing ability, signal transduction, and nanodomain formation.