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cis-4-methylsphingosine

cis-4-methylsphingosine A86478 (Previously 860478) cis-4-methylsphingosine

cis-4-methylsphingosine

cis-4-methylsphingosine (cis-4M-Sph) is a synthetic sphingosine analogue that is readily taken up by cells and interacts with S1P receptors through its metabolite cis-4M-S1P in a manner similar to FTY720. cis-4M-Sph interacts primarily with the S1P receptors S1P(2) and S1P(3), and only weakly with S1P(1). cis-4M-Sph induces apoptosis of neuroblastoma cells.

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