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CER1(d18:1/28:0/18:2)

CER1(d18:1/28:0/18:2) 860861 N-[28-linoleoyloxy octacosanoyl]-D-erythro-sphingosine

CER1(d18:1/28:0/18:2)

N-[28-linoleoyloxy octacosanoyl]-D-erythro-sphingosine, or CER1(d18:1/28:0/18:2), is a specialized sphingolipid essential for maintaining skin barrier integrity and hydration. As a key component of the stratum corneum (SC)—the outermost layer of the skin—ceramides play a vital role in regulating water retention and protecting against environmental stressors. The lipid matrix of the SC is primarily composed of ceramides, free fatty acids, and cholesterol, which form a highly organized structure that prevents excessive transepidermal water loss.

Dysfunction in ceramide composition has been linked to a number of dermatological conditions, including lamellar ichthyosis, atopic dermatitis, and psoriasis. 

With over 50 years of expertise in lipid and sphingolipid innovation, Avanti ensures the highest purity and consistency to empower researchers in their discoveries.

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Effective March 1, 2018, Merck KGaA, Darmstadt, Germany* is the exclusive Distributor of Avanti Research. Research Products for all countries except the United States. For product pricing and order placement, please click on the appropriate location button below.

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*The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the U.S. and Canada

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