18:0 PEG2000 PE (Ammonium Salt) A80120 (Previously 880120) 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

18:0 PEG2000 PE, or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt), is a high-purity, synthetic phospholipid conjugated with polyethylene glycol (PEG). This PEGylated phospholipid consists of distearoylphosphatidylethanolamine (DSPE) and methoxy-terminated PEG with a molecular weight of 2000. The ammonium salt form improves this phospholipid’s aqueous solubility and is ideal for incorporating into liposomal formulations and other drug delivery systems.

The lipid provides steric stabilization of liposomes, enhancing circulation time and reducing recognition by the reticuloendothelial system (RES).

First name

Please provide your first name

Last name

Please provide your last name

Please provide an email address

Organisation/company

Please provide your organisation/company name

Special packaging request

Please provide your special packaging request

Quantity

A quantity is required

00000000

$0.00

Buy

Product details

Product Type

Lipids

Product Category

Polymers & Polymerizable Lipids - mPEG Phospholipids - 2000

Application

18:0 PEG2000 PE plays a pivotal role in the formulation of long-circulating, stealth liposomes designed to evade rapid immune clearance. It is widely used in drug and gene delivery systems where stability and extended circulation are highly important. By modifying the surface of nanoparticles, this phospholipid minimizes opsonization and improves biodistribution. This makes it an invaluable component for targeted therapies. Researchers rely on 18:0 PEG2000 PE to develop PEGylated liposomes that improve drug efficacy; its integration into lipid nanoparticles (LNPs) supports advancements in mRNA and RNA-based delivery systems.

Data

Hygroscopic	Yes
Light sensitive	No
Molecular formula	C₁₃₃H₂₆₇N₂O₅₅P (average FW due to polydispersity of PEG)
Percent composition	C 56.94%, H 9.59%, N 1.00%, O 31.36%, P 1.10%
Purity	>99%
Stability	1 Years
Storage temperature	-20°C
CAS number	474922-77-5 CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula weight	2805.5
Exact mass	2803.53
Synonyms	DSPE-mPEG(2000) DSPE-PEG2000 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-methoxy(polyethylene glycol)-2000] (ammonium salt) 770120
Transition temperature	12.8°C (melting transition in micelles)
Solubility in different solvents	Soluble in ethanol at 5mg/mL, soluble in DMSO at 5mg/mL, soluble in Chloroform:Methanol (85:15) at 5mg/mL

Certificates of Analysis

880120 - ChemDraw File
English: 16.0 KB

ChemDraw File

Download

880120C - Safety Data Sheet
English: 271.0 KB

Safety Data Sheet

Download
880120P - Safety Data Sheet
English: 287.0 KB

Safety Data Sheet

Download

Name	Typical content	Expires
cookieConsent	Used to check if your device accepts cookies and used to remember users cookie consent.	1 year
ASP.NET_SessionId	This cookie is used by ASP.NET to maintain an anonymous user session by assigning a unique session ID. It enables the website to store temporary information between pages, such as login status or form input.	End of session
commerceCart	Used to store items added to a cart by an anonymous user. Contents are serialized.	7 days
.AspNet.Cookies	This cookie is used to identify and authenticate logged-in users. It maintains secure sessions by storing an encrypted authentication token.	30 days
SC_ANALYTICS_GLOBAL_COOKIE	This analytics cookie is provided by Sitecore. It tracks a visitor’s multiple visits to our Website in one year. We use this information to help improve our Website. This cookie is not used to identify individuals using the Website.	10 Years
sitename#lang	This cookie is provided by Sitecore. This cookie tracks a user's language selection. The name of the cookie varies based on the configured site name	End of Session
shell#lang	This cookie is provided by Sitecore. This cookie tracks a user's language selection. The name of the cookie varies based on the configured site name	End of Session
__RequestVerificationToken	An anti forgery token used to help prevent CSRF attacks.	End of Session
_form_goals	Used to check if you have previously complete a form.	2 years
lastShownMarketingConsentDate_{identifier}	Use to determine when we requested you review your marketing consent for your account. It helps ensure we limit prompting to review your marketing consent, improving user experience.	1 year
mailinglistsignupbanner_{identifier}	Use to determine when whether a mailing list sign up form has been already shown within a time period. It helps ensure that users are not repeatedly prompting or shown sign up forms, improving user experience. We may create multiple cookies with different identifiers.	< 120 days
productFinderLastSearch	Used within our product finder to determine the last search performed.	1 year
purchaseRegion	This cookie will be used to determine the purchase region	30 days
VISITOR_PRIVACY_METADATA	YouTube sets this cookie to store the user's cookie consent state for the current domain.	6 months

Name	Typical content	Expires
recentlyViewedItems	Contains a list of recently visited items including products or formulations.	30 days
li_gc	Used by LinkedIn to store consent of guests regarding the use of cookies for non-essential purposes.	6 months
lidc	Used by LinkedIn for routing.	24 hours
__Secure-1PAPISID	Essential for maintaining your logged-in state (session) and authenticating you across different Google services securely.	2 years
__Secure-1PSID	Set by Google, this cookie works alongside others to verify your identity and keep you signed in to your Google account securely.	2 years
__Secure-1PSIDCC	A crucial security cookie used by Google to confirm the authenticity of the user's session, helping to protect users data from unauthorised access.	1 year
_bioz_depot_session	Bioz.com	Session

Name	Typical content	Expires
_gat	Used by Google Analytics to throttle request rate.	10 minutes
_ga	Contains a unique identifier used by Google Analytics to determine unique visitors to our website.	2 years
_clsk	Used by Microsoft Clarity to connect multiple page views by a user into a single Clarity session recording.	1 day
_clck	Persists the Microsoft Clarity User ID and preferences, unique to that site is attributed to the same user ID.	1 year
YSC	YSC cookie is set by Youtube and is used to track the views of embedded videos on Youtube pages.	Session
_uetsid	Bing Ads sets this cookie to engage with a user that has previously visited the website.	1 day
_uetvid	Bing Ads sets this cookie to engage with a user that has previously visited the website.	1 year 24 days
__Secure_ROLLOUT_TOKEN	Used by YouTube to manage feature rollout and experimentation. It helps Google control which new features or interface changes are shown to users as part of testing and staged rollouts, ensuring consistent experience for a given user during an experiment.	6 months
__Secure_YEC	Used to detect spam, fraud, and abuse to protect advertisers and YouTube creators	13 months

Name	Typical content	Expires
ANONCHK	Used by Microsoft Clarity and Microsoft Ads to store session ID for a users session to ensure that clicks are verified for reporting purposes and for personalisation.	10 mins
MUID	Identifies unique web browsers used by Microsoft. These cookies are used for advertising, site analytics, and other operational purposes.	1 year
SM	Used by Microsoft to synchronise the unique identifier across Microsoft domains for consistent user recognition and ad targeting.	End of session
MR	Used by Microsoft to support ad delivery and performance tracking.	7 days
CLID	Used by Microsoft Clarity to identify the first time a user visited any site using Clarity. Helps track user behaviour and engagement across sessions for analytics purposes.	1 year
AEC	Used by Google to ensure that requests during a browsing session are genuinely made by the user, helping to prevent malicious activity such as cross-site request forgery.	6 months
NID	Set by Google to store user preferences and personalise content, including ads on Google services. Also supports services like reCAPTCHA and SafeSearch settings.	6 months
IDE	Set by Google (DoubleClick), this cookie helps show relevant ads to users and measure the success of advertising campaigns.	13 months
DSID	Set by Google, this cookie remembers a user’s ad preferences and identifies when they are signed in on non-Google sites.	7–14 days
__Secure-3PAPISID	Set by Google, this cookie helps deliver personalised adverts based on a user’s browsing history and profile.	2 years
__Secure-3PSID	Set by Google, this cookie works with others to show targeted adverts on third-party websites.	2 years
__Secure-3PSIDCC	Set by Google, this cookie helps prevent advertising fraud and ensures adverts are shown securely and reliably.	1 year
__Secure-3PSIDTS	Set by Google, this cookie tracks when users interact with ads and content for better ad performance measurement.	2 years
sa_user_id	StackAdapt sets this cookie as a third party advertising cookie to record information about a user's website activity, such as the pages visited and the locations viewed, to enable us to provide users with interest-based content and personalised advertisements on external websites.	1 year
sa_user_id_v2	StackAdapt sets this cookie as a third party advertising cookie to record information about a user's website activity, such as the pages visited and the locations viewed, to enable us to provide users with interest-based content and personalised advertisements on external websites.	1 year
sa_user_id_v3	StackAdapt sets this cookie as a third party advertising cookie to record information about a user's website activity, such as the pages visited and the locations viewed, to enable us to provide users with interest-based content and personalised advertisements on external websites.	1 year
bcookie	LinkedIn sets this cookie from LinkedIn share buttons and ad tags to recognise browser IDs.	1 year

Explore similar products

Avanti™ DSPE-PEG2000

14:0 PEG2000 PE

16:0 PEG2000 PE

18:0 PEG2000 PE (Sodium Salt)