DSPE-PEG(2000) Carboxy NHS 880138 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000, NHS ester] (sodium salt)
DSPE-PEG (2000) Carboxy NHS is a 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) with attached polyethylene glycol (PEG), containing active carboxy N-Hydroxysuccinimide ester (NHS). It’s a linear heterobifunctional self-assembling reagent to prepare PEGylated liposomes or micelles, while also providing an NHS group for conjugation with amine-containing molecules.
It’s one of the most commonly used reactive phospholipids in targeted drug delivery to modulate the lipid bilayer and thus improve drug solubility. The compound is also often used to conjugate proteins, antibodies, peptides, and other substrates.
As a PEGylated phospholipid, DSPE-PEG (2000) Carboxy NHS has a longer blood circulation time and higher stability and demonstrates amphipathic properties.
Avanti Research creates quality DSPE-PEG (2000) Carboxy NHS lab reagent with high purity and excellent chemical reactivity for a range of lipid-oriented studies.
