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N-TETAMINE-pSar45-Folate

N-TETAMINE-pSar45-Folate A88148 (Previously 880148) N-TETAMINE-pSar45-Folate

N-TETAMINE-pSar45-Folate
N-TETAMINE-pSar45-folate is a lipid that is composed of a folate unit conjugated to a N-TETAMINE-pSar45. Polysarcosine (pSar) lipids are offered as alternatives to traditional PEGylated lipids used in RNA delivery vehicles. Compared to similar PEGylated lipid nanoparticles (LNPs), pSar LNPs have shown improved mRNA transfection potency and improved safety profiles. The folate group is an invaluable functional group in targeted drug delivery to cancer cells. This is because the large amount of folate receptors on cancer cells. By conjugating folate onto this lipid, it allows targeted drug delivery to cancer cells.
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