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DSPE-PEG8 Maleimide

DSPE-PEG8 Maleimide A88249 (Previously 880249) 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(octaethylene glycol)] (sodium salt)

DSPE-PEG8 Maleimide

DSPE-PEG8 maleimide is a monodispersed, low molecular weight PEG lipid designed to support targeted drug delivery using lipid nanoparticles (LNPs). With an 8-unit PEG spacer and a reactive maleimide group, this functionalized lipid provides a reliable way to conjugate peptides or proteins with free thiol groups directly to the surface of LNPs.

By enabling this kind of site-specific attachment, DSPE-PEG8 maleimide helps researchers create more targeted delivery systems—improving cellular uptake and therapeutic precision. It’s a great option for anyone working on LNP formulations for mRNA delivery, gene editing, vaccines, or other applications where targeting really matters.

This PEG lipid offers the purity and performance you need for reproducibility in research and early development.

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Effective March 1, 2018, Merck KGaA, Darmstadt, Germany* is the exclusive Distributor of Avanti Research. Research Products for all countries except the United States. For product pricing and order placement, please click on the appropriate location button below.

For customers located outside the United States, you will be redirected to www.sigmaaldrich.com/avanti prior to completing your purchase. Thank you for your continued business and support of Avanti Research!

*The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the U.S. and Canada

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