Chelators

790981 14:0 PE-DTPA (Gd)

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790535 14:0 PE-DTPA

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790408 16:0 DGS-NTA(Ni)

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790106 16:0 PE-DTPA

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850868 18:0 Caproylamine PE-N-DOTA, sodium salt

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850869 18:0 Caproylamine PE-N-DOTA(Gd)

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791275 18:0 PE-DTPA (Gd)

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791300 18:0 PE-DTPA

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790528 18:1 DGS-NTA

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791113 18:1 DGS-NTA(Co)

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790404 18:1 DGS-NTA(Ni)

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791297 bis(14:0 PE)-DTPA (Gd)

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850864 DOPE-DOTA (Gd)

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850865 DOPE-DOTA, sodium salt

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850867 DSPE-DOTA, sodium salt

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791268 DTPA-BSA (Gd)

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The incorporation of metal-chelating lipids into nanolipoprotein particles (NLPs) has been studied. NLPs are nanometer-sized particles that self-assemble from apolipoprotein and phospholipid. The nanometer size and functionalization of these NLPs suggest their application as carriers of recombinant proteins. Nickel (Ni) and Gadolinium (Gd) have successfully been shown to sequester histidine (his)-tagged proteins dependent on the size and compilation of the NLPs. Avanti offers lipids chelated with Ni, Gd, cobalt (Co), and copper (Cu), as well as the non-chelated lipids. Check out our lipid chelators!

Fischer, Nicholas O.; Blanchette, Craig D.; Chromy, Brett A.; Kuhn, Edward A.; Segelke, Brent W.; Corzett, Michele; Bench, Graham; Mason, Peter W.; Hoeprich, Paul D. Immobilization of His-Tagged Proteins on Nickel-Chelating Nanolipoprotein Particles. Bioconjugate Chemistry; 20: 460-465.

Headgroup Modified Lipids

Explore Headgroup Modified Lipids from Avanti Research

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Functionalized Lipids

Avanti offers several types of functionalized lipids to study drug delivery, transfection, reporter molecules, and structural biology. Full list here.

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