Chelators

A89981 14:0 PE-DTPA (Gd)

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A89535 14:0 PE-DTPA

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A89408 16:0 DGS-NTA(Ni)

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A89106 16:0 PE-DTPA

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A85868 18:0 Caproylamine PE-N-DOTA, sodium salt

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A85869 18:0 Caproylamine PE-N-DOTA(Gd)

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A89275 18:0 PE-DTPA (Gd)

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A89300 18:0 PE-DTPA

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A89528 18:1 DGS-NTA

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A89113 18:1 DGS-NTA(Co)

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A89404 18:1 DGS-NTA(Ni)

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A89297 bis(14:0 PE)-DTPA (Gd)

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A85864 DOPE-DOTA (Gd)

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A85865 DOPE-DOTA, sodium salt

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A85867 DSPE-DOTA, sodium salt

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A89268 DTPA-BSA (Gd)

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The incorporation of metal-chelating lipids into nanolipoprotein particles (NLPs) has been studied. NLPs are nanometer-sized particles that self-assemble from apolipoprotein and phospholipid. The nanometer size and functionalization of these NLPs suggest their application as carriers of recombinant proteins. Nickel (Ni) and Gadolinium (Gd) have successfully been shown to sequester histidine (his)-tagged proteins dependent on the size and compilation of the NLPs. Avanti offers lipids chelated with Ni, Gd, cobalt (Co), and copper (Cu), as well as the non-chelated lipids. Check out our lipid chelators!

Fischer, Nicholas O.; Blanchette, Craig D.; Chromy, Brett A.; Kuhn, Edward A.; Segelke, Brent W.; Corzett, Michele; Bench, Graham; Mason, Peter W.; Hoeprich, Paul D. Immobilization of His-Tagged Proteins on Nickel-Chelating Nanolipoprotein Particles. Bioconjugate Chemistry; 20: 460-465.

Headgroup Modified Lipids

Explore Headgroup Modified Lipids from Avanti Research

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Functionalized Lipids

Avanti offers several types of functionalized lipids to study drug delivery, transfection, reporter molecules, and structural biology. Full list here.

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