DSPE-DOTA, sodium salt 850867 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt

DSPE DOTA is a chelator lipid that serves as a key contrast agent in magnetic resonance imaging (MRI). Applications of DSPE DOTA include cancer detection by highlighting tumors through enhanced blood supply, brain imaging to identify disrupted blood-brain barriers indicative of neurological conditions like stroke or tumors, arterial imaging to assess abnormalities such as aneurysms or plaque buildup, joint imaging for evaluating inflammation in arthritis, and liver imaging for assessing function and detecting lesions. Adjusting the DOTA structure, linker flexibility, and complex size allows for sensitivity optimization. Avanti offers a series of DOTA lipids with different linkers and fatty acid composition for research in this area.