Light Plasma Ceramide SPLASH™ 330843 Light Plasma Ceramide SPLASH™ Internal Standard for Lipidomic Analysis

Light Plasma Ceramide SPLASH is the non-deuterated complement to our Plasma Ceramide SPLASH™. It contains the exact same clinically relevant ceramide species at the same biological ratios found in human plasma, but without deuterium labels. This mixture serves as an ideal primary standard for assay optimization, retention time confirmation, and the generation of external calibration curves.  

Ceramides are increasingly recognized as critical bioactive lipids and potent biomarkers for cardiovascular disease, insulin resistance, and type 2 diabetes. Elevated concentrations of specific plasma ceramides have been shown to predict major adverse cardiac events and mortality more accurately than LDL cholesterol alone.  

Plasma Ceramide SPLASH™ was created to address the need for a precise, clinically relevant internal standard mixture for this vital lipid class. This ready-to-use standard contains deuterium-labeled ceramide species at concentrations that mimic the specific ratios found in human plasma. By providing a comprehensive set of internal standards in a single vial, Plasma Ceramide SPLASH™ enables researchers to account for extraction losses and ionization differences, ensuring the accurate quantitation necessary for translational lipidomics and biomarker discovery.