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Cholic acid-d4

Cholic acid-d4 A83256 (Previously 330256) 5ß-cholanic acid-3a,7a,12a-triol (2,2,4,4-d4)

Cholic acid-d4

This product is for research use only in bile acid profiling, lipid metabolism, and analytical validation.

Cholic acid-d₄ is a deuterium-labeled analog of cholic acid designed for high-precision mass spectrometry and NMR-based lipidomics. It offers excellent spectral resolution and minimal chromatographic shift thanks to four non-exchangeable hydrogen atoms replaced by deuterium.

This deuterated substitution provides a more accurate quantification of endogenous cholic acid in complex biological matrices such as serum, plasma, bile, and feces.

As a primary bile acid synthesized in hepatocytes through cholesterol metabolism, cholic acid is critical in emulsifying dietary fats, eliminating excess cholesterol, and modulating gut microbiota activity.

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