TopFluor™ PC 810281 1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phosphocholine

TopFluor™ PC, or 1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phosphocholine, is a specialized phospholipid with a fluorescence label that is used extensively in cell membrane studies and fluorescence microscopy. Phosphatidylcholines (PC) are the building blocks of eukaryotic membranes and are an important component of the colon's mucosal layer. As such, PC is a strong bilayer-forming lipid.

The TopFluor™ label is a green fluorescent probe attached to the phospholipid molecule that allows researchers to visualize and track the behavior of lipids in biological systems.

Avanti’s TopFluor™ PC is distinguished by its superior quality (>99% purity) and rigorous testing. Avanti Research supports researchers with expert guidance on product application to maximize your research outcomes.

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Product details

Product Type

Lipids

Product Category

Fluorescent Lipids & Probes - TopFluor™ Derivatives - Phospholipids

Application

TopFluor™ PC shows promise in various experimental applications relating to fluorescent studies. It has been effectively used in the formation of small unilamellar vesicles, providing a reliable model for studying membrane biophysics. It's also been utilized in the preparation of unilamellar phospholipid liposomes. These liposomes are essential for investigating lipid-protein interactions and drug delivery systems. Additionally, its fluorescent properties make it an excellent choice for tracking lipid movement and distribution within cells to help develop targeted therapeutic strategies. Furthermore, phosphatidylcholine functions as a surfactant in the mucosal layer by creating a hydrophobic surface that inhibit bacterial penetrance and infection. This makes TopFluor™ PC a valuable asset in research focused on understanding and enhancing mucosal barrier functions. It can also be used to treat fat embolism, giving it a significant role in medical applications, as well.

Data

Hygroscopic	No
Light sensitive	Yes
Molecular formula	C₄₈H₈₃BF₂N₃O₈P
Percent composition	C 63.36%, H 9.19%, B 1.19%, F 4.18%, N 4.62%, O 14.07%, P 3.40%
Purity	>99%
Stability	1 Year
Storage temperature	-20°C
CAS number	1246355-63-4 CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula weight	909.969
Exact mass	909.598
Synonyms	1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phosphocholine
Ex/Em	495/503nm

Certificates of Analysis

810281 - ChemDraw File
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ChemDraw File

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810281C - Safety Data Sheet
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Safety Data Sheet

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810281P - Safety Data Sheet
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Safety Data Sheet

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