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MAPCHO™-12

MAPCHO™-12 A80336 (Previously 850336) n-dodecylphosphocholine

MAPCHO™-12

MAPCHO™-12, or n-dodecyl-β-D-maltopyranoside, is a zwitterionic detergent designed for the efficient solubilization, stabilization, and structural analysis of membrane proteins. It features a 12-carbon dodecyl chain linked to a phosphocholine headgroup and closely mimics the natural lipid environment of biological membranes.

With a critical micelle concentration (CMC) of approximately 1.5 mM, MAPCHO™-12 forms highly stable micelles and offers a mild but effective solubilization environment. It also prevents denaturation and aggregation to ensure proteins remain functional throughout experimentation.

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