CP-LC-1254 860807 2-hexyldecyl 2-((2-(dimethylamino)ethyl)carbamoyl)-4-((3-((2-hexyldecyl)oxy)-3-oxopropyl)thio)butanoate
Manufactured and Distributed under License from Certest Biotec S.L
CP-LC-1254 is an ionizable lipid that successfully encapsulates mRNA. In vivo studies carried out in mice show that lipid nanoparticle (LNP) formulations using ionizable lipid CP-LC-1254 exhibit comparable mRNA expression and favorable safety profiles compared to industry leading formulations in the industry. LNPs formulated with CP-LC-1254 have shown a primary biodistribution in the spleen and exhibit high endosomal escape.