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KRN7000 A86000 (Legacy code 867000) α-Galactosyl Ceramide
KRN7000 is a synthetic analog of α-galactosylceramide and the marine natural product agelasphin. It is a specific ligand for human and mouse NKT cells and remains the best studied ligand of the lipid-binding MHC class I-like protein CD1d. KRN7000 protects against LPS-induced shock and displays potent antitumor activity in various in vivo models.