DSPE-PEG2K-triGalNAc A88157 (Previously 880157) 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]-N-tri(N-acetylgalactosamine), ammonium salt
Patent pending
Representative Structure
The molecular weight and exact mass are averages based on the polydispersity of PEG.
DSPE-PEG2K-triGalNAc is a functionalized PEG lipid that enhances targeted drug delivery by binding to the Asialoglycoprotein Receptor (ASGPR) which are predominantly found on the surface of liver cells. By functionalizing DSPE-PEG2K with triGalNac, it allows this PEG lipid to be used in the formation of liposomes or LNPs that target the liver for drug delivery.