DChemsPC 880346 1,2-dicholesterylhemisuccinoyl-sn-glycero-3-phosphocholine
Cholesterol exchange is a major reason for the instability of liposomes in blood. The formation of a covalent hybrid between cholesterol and glycerophosphocholine preserves the bilayer-stabilizing effect of free cholesterol but prevents its transfer from the bilayer. Thus, disterolphospholipids are valuable new components for liposome formulation.
