Saturated Fatty Acid

850302 03:0 PC

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850303 04:0 PC

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850305 06:0 PC (DHPC)

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850306 07:0 PC (DHPC)

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850315 08:0 PC

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850320 09:0 PC

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850325 10:0 PC

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850330 11:0 PC

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850335 12:0 PC (DLPC)

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850340 13:0 PC

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850345 14:0 PC (DMPC)

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850350 15:0 PC

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850333 16:0 2-PC

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850355 16:0 PC (DPPC)

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850360 17:0 PC

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850365 18:0 PC (DSPC)

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850367 19:0 PC

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850368 20:0 PC

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850370 21:0 PC

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850371 22:0 PC

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850372 23:0 PC

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850373 24:0 PC

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850860 Thio-DMPC

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PC & LPC

Phosphatidylcholine (PC) was first found to be a component of egg yolk and originally called “lecithin”. PC is the most abundant phospholipid in cells and positively influences the incorporation of cholesterol in membranes. Sphingomyelin synthesis is also dependent on its PC precursor. PC has been linked to several biological processes including intracellular cholesterol transport and membrane cholesterol homeostasis. Other roles include membrane-mediated cell signaling and PCTP activation of enzymes.

Lysophosphatidylcholine (LPC) has increasingly gained recognition as a factor associated with cardiovascular and neurodegenerative diseases. LPC is primarily produced by PC turnover via phospholipase A2. LPC is recycled to PC when Acyl-CoA is available in the presence of lysophosphatidylcholine acyltransferase (LPCAT). Research is currently being conducted to better understand enzyme kinetics and LPC metabolism to identify possible therapeutic targets for LPC-associated diseases.

Lagace TA. Phosphatidylcholine: Greasing the Cholesterol Transport Machinery. Lipid Insights. 2016;8(Suppl 1):65-73. Published 2016 Apr 4. doi:10.4137/LPI.S31746

Law SH, Chan ML, Marathe GK, Parveen F, Chen CH, Ke LY. An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases. Int J Mol Sci. 2019;20(5):1149. Published 2019 Mar 6. doi:10.3390/ijms20051149

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Saturated Fatty Acid

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Phospholipids

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