Saturated Fatty Acid

A85302 03:0 PC

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A85303 04:0 PC

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A85305 06:0 PC (DHPC)

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A85306 07:0 PC (DHPC)

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A85315 08:0 PC

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A85320 09:0 PC

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A85325 10:0 PC

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A85330 11:0 PC

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A85335 12:0 PC (DLPC)

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A85340 13:0 PC

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A80345 14:0 PC (DMPC)

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A85350 15:0 PC

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A85333 16:0 2-PC

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A80355 16:0 PC (DPPC)

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A85360 17:0 PC

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A80365 18:0 PC (DSPC)

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A85367 19:0 PC

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A85368 20:0 PC

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A85370 21:0 PC

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A85371 22:0 PC

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A85372 23:0 PC

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A85373 24:0 PC

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A85860 Thio-DMPC

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PC & LPC

Phosphatidylcholine (PC) was first found to be a component of egg yolk and originally called “lecithin”. PC is the most abundant phospholipid in cells and positively influences the incorporation of cholesterol in membranes. Sphingomyelin synthesis is also dependent on its PC precursor. PC has been linked to several biological processes including intracellular cholesterol transport and membrane cholesterol homeostasis. Other roles include membrane-mediated cell signaling and PCTP activation of enzymes.

Lysophosphatidylcholine (LPC) has increasingly gained recognition as a factor associated with cardiovascular and neurodegenerative diseases. LPC is primarily produced by PC turnover via phospholipase A2. LPC is recycled to PC when Acyl-CoA is available in the presence of lysophosphatidylcholine acyltransferase (LPCAT). Research is currently being conducted to better understand enzyme kinetics and LPC metabolism to identify possible therapeutic targets for LPC-associated diseases.

Lagace TA. Phosphatidylcholine: Greasing the Cholesterol Transport Machinery. Lipid Insights. 2016;8(Suppl 1):65-73. Published 2016 Apr 4. doi:10.4137/LPI.S31746

Law SH, Chan ML, Marathe GK, Parveen F, Chen CH, Ke LY. An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases. Int J Mol Sci. 2019;20(5):1149. Published 2019 Mar 6. doi:10.3390/ijms20051149

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Saturated Fatty Acid

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