16:0 PC (DPPC) A80355 (Previously 850355) 1,2-dipalmitoyl-sn-glycero-3-phosphocholine

1,2-dipalmitoyl-sn-glycero-3-phosphocholine, or 16:0 PC (DPPC), is a fully saturated phospholipid with two 16-carbon acyl chains. This phospholipid is known for its critical role in liposomal formulations, pulmonary surfactant research, and advanced drug delivery systems. As such, DPPC is essential in both biomedical and pharmaceutical applications.

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Product details

Product Type

Lipids

Product Category

Phospholipids - PC & LPC - Saturated Fatty Acid

Application

Applications for 16:0 PC (DPPC) include being used as a major component of lung surfactants, as it plays a significant role in respiratory function and neonatal treatments to ensure proper alveolar stability. Researchers have also noted its role in enhancing the stability and controlled release of liposomal drug delivery systems, which helps improve bioavailability and efficacy. Because of its high transition temperature, DPPC is one of the preferred lipids for analyzing thermotropic and mechanical properties in synthetic bilayer systems. Additionally, its well-characterized phase behavior makes it suitable for utilization in lipid bilayer formation, protein-lipid interaction analysis, and thermotropic studies.

Data

Hygroscopic	No
Light sensitive	No
Molecular formula	C₄₀H₈₀NO₈P
Percent composition	C 65.45%, H 10.98%, N 1.91%, O 17.44%, P 4.22%
Purity	>99%
Stability	1 Year
Storage temperature	-20°C
CAS number	63-89-8 CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula weight	734.039
Exact mass	733.562
Synonyms	1,2-dihexadecanoyl-sn-glycero-3-phosphocholine DPPC PC(16:0/16:0) 738555
Transition temperature	41°C
Solubility in different solvents	Insoluble in DMSO, soluble in ethanol and Chloroform:Methanol:Water (65:25:4) at 5mg/mL
CMC	0.46nM

Certificates of Analysis

850355 - ChemDraw File
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ChemDraw File

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850355C - Safety Data Sheet
English: 298.0 KB

Safety Data Sheet

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