NovoArc/Archaeal Tetraether Lipids

Avanti Research, in partnership with NovoArc, introduces archaeal tetraether lipids—a new class of lipids designed to support lipid nanoparticle (LNP) and liposome development. These lipids feature membrane-spanning structures and ether bond chemistry that provide enhanced stability compared to conventional phospholipids.

Engineered for improved formulation durability and delivery performance, archaeal tetraether lipids help protect payloads under thermal, oxidative, and pH stress while supporting applications in nucleic acid delivery, oral therapeutics, and PEG-free liposome design.

Through the Avanti Research and NovoArc collaboration, researchers gain access to innovative lipid tools that expand formulation flexibility and enable more resilient delivery systems.