Chelators

A89981 (790981) 14:0 PE-DTPA (Gd)

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A89535 (790535) 14:0 PE-DTPA

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A89408 (790408) 16:0 DGS-NTA(Ni)

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A89106 (790106) 16:0 PE-DTPA

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A85868 (850868) 18:0 Caproylamine PE-N-DOTA, sodium salt

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A85869 (850869) 18:0 Caproylamine PE-N-DOTA(Gd)

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A89275 (791275) 18:0 PE-DTPA (Gd)

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A89300 (791300) 18:0 PE-DTPA

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A89528 (790528) 18:1 DGS-NTA

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A89113 (791113) 18:1 DGS-NTA(Co)

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A89404 (790404) 18:1 DGS-NTA(Ni)

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A89297 (791297) bis(14:0 PE)-DTPA (Gd)

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A85864 (850864) DOPE-DOTA (Gd)

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A85865 (850865) DOPE-DOTA, sodium salt

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A85867 (850867) DSPE-DOTA, sodium salt

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A89268 (791268) DTPA-BSA (Gd)

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The incorporation of metal-chelating lipids into nanolipoprotein particles (NLPs) has been studied. NLPs are nanometer-sized particles that self-assemble from apolipoprotein and phospholipid. The nanometer size and functionalization of these NLPs suggest their application as carriers of recombinant proteins. Nickel (Ni) and Gadolinium (Gd) have successfully been shown to sequester histidine (his)-tagged proteins dependent on the size and compilation of the NLPs. Avanti offers lipids chelated with Ni, Gd, cobalt (Co), and copper (Cu), as well as the non-chelated lipids. Check out our lipid chelators!

Fischer, Nicholas O.; Blanchette, Craig D.; Chromy, Brett A.; Kuhn, Edward A.; Segelke, Brent W.; Corzett, Michele; Bench, Graham; Mason, Peter W.; Hoeprich, Paul D. Immobilization of His-Tagged Proteins on Nickel-Chelating Nanolipoprotein Particles. Bioconjugate Chemistry; 20: 460-465.

Headgroup Modified Lipids

Explore Headgroup Modified Lipids from Avanti Research

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Functionalized Lipids

Avanti offers several types of functionalized lipids to study drug delivery, transfection, reporter molecules, and structural biology. Full list here.

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